哀莫大于心死

哀莫大於心死
āimòdàyúxīnsǐ
  1. nothing sadder than a withered heart (idiom attributed to Confucius by Zhuangzi 庄子 Zhuāngzǐ)
  2. no greater sorrow than a heart that never rejoices
  3. the worst sorrow is not as bad as an uncaring heart
  4. nothing is more wretched than apathy

CEDICT

Despair is the greatest sorrow; Nothing gives greater cause for sorrow than despair; There is no grief so great as despair; There is no poverty like the poverty of spirit.

Wiktionary

一个人最可悲的事莫过于丧失了良知灵魂，变得麻木不仁。

重編國語辭典

丧失人格和自信心是最可悲的事情

維基詞典

Entry Composition

1 哀 āi
  1. (bound form) sorrow; grief; pity
  2. (bound form) to grieve for; to pity; to lament; to condole
2 莫大 mòdà
  1. greatest
  2. most important
=3 于 yú
  1. to go
  2. to take
  3. sentence-final interrogative particle
  4. variant of 于 yú
=3 于 yú
  1. (of time or place) in; at; on
  2. (indicating any indirect relation) to; toward; vis-à-vis; with regard to; for
  3. (indicating a source) from; out of
  4. (used in comparison) than
  5. (used in the passive voice) by
4 心 xīn
  1. heart
  2. mind
  3. intention
  4. center
  5. core

classifiers: 顆, 個
5 死 sǐ
  1. to die
  2. impassable
  3. uncrossable
  4. inflexible
  5. rigid
  6. extremely
  7. damned